The Marrow Cellution Bone Marrow Aspiration Harvesting System is a novel bone marrow access and retrieval device that incorporates features designed to minimise the limitations of traditional trocar needles.
Marrow Cellution maximises stem and progenitor cell recovery while minimising peripheral blood infiltration. Because fluid under force follows the path of least resistance, trocar needles with side ports aspirate primarily through the distal end of
the cannula. This leads to excessive blood collection, requiring additional manipulation, i.e., centrifugation which is referred to as Bone Marrow Aspirate Concentrate - BMAC.
Marrow Cellution accesses aspirate flow collected exclusively laterally as the tip of the aspiration cannula is closed allowing marrow collection perpendicular to and around the channel created by the device. It incorporates technology to precisely reposition the retrieval cannula within the marrow space after each aspiration. These features achieve a clinicians‘ desire for a single entry point.
A single puncture with Marrow Cellution device provides high quality bone marrow aspirate and cancellous bone graft, collected from the site within the marrow geography.
Marrow Aspiration, Minimal Manipulation
The Marrow Cellution Bone Marrow Aspiration System is intended for use for aspiration of bone marrow or autologous blood. It allows the user to aspirate in a measured and controlled manner over a large geography within the marrow space. Marrow Cellution draw device occurs via an 11 Gauge diameter introducer needle, sharp and blunt stylet, and aspiration cannula via a 10ml syringe. Marrow Cellution is designed for use in the Iliac Crest or Tibia.
What are the Limitations of a Traditional Needle?
Traditional bone marrow aspiration needles aspirate primarily through an open-ended cannula, which leads to excess peripheral blood dilution and inadequate collection of key stem and progenitor cells. For this reason, a high volume of bone marrow aspirate must be collected and then manipulated (i.e., centrifuged) before being applied for regenerative therapies.
How Does the Marrow Cellution System Overcome These Limitations?
The unique design of the Marrow Cellution system offers two key features that are not capable with a traditional needle:
1. Closed-tip aspiration cannula that restricts aspiration through the side holes of the cannula and away from the channel caused by the tip of the needle, avoiding excess peripheral blood infiltration.
2. A mechanical means for measured, controlled retraction of the aspiration cannula to collect bone marrow aspirate from multiple geographies inside the medullary space with a single puncture.
Marrow Aspiration System and Related Concentrations of Stem and Progenitor Cells: White Paper Review